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Shout Active Enzyme Laundry Stain Remover Spray – Gentle Yet Powerful Stain Removal for Sensitive Family Laundry

Shout Active Enzyme Laundry Stain Remover Spray – Gentle Yet Powerful Stain Removal for Sensitive Family Laundry

Regular price $5.82 USD
Regular price $10.26 USD Sale price $5.82 USD -43%
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Why you'll love it

  • Triple-acting formula (clings, penetrates, lifts) tackles a wide range of everyday and tough stains in one product
  • 50x concentration vs. in-wash powder means less product needed per treatment, delivering better value
  • Flexibility to treat now and wash up to a week later removes pressure during busy weeks
  • Safe for all colorfast fabrics and all water temperatures, eliminating guesswork and separate products for whites vs. colors
  • Compatible with both HE and standard washers, so renters and homeowners can use the same product
  • Pack of 6 option offers significant savings for high-volume laundry households

Perfect for

  • Pre-treating set-in food, drink, and blood stains before a regular wash cycle
  • Spray-treating kids' grass and dirt stains at the end of a play day
  • Treating red wine or makeup spills on tablecloths and clothing up to a week before laundering
  • Refilling smaller spray bottles for daily spot-treatment use around the home
  • Bulk stain management for high-volume laundry environments like daycares or rental properties


REMOVE STAINS THE FIRST TIME – Guaranteed or it’s free.


TOUGH ON EVERYDAY STAINS – Works on a wide range of stains including food, grass, dirt and blood.


GENTLE ON FABRICS – Safe for your colorfast washables in all water temperatures.


STAIN FIGHTING INGREDIENTS – Treat stains now and wash up to a week later.

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Product Information
What You'll Get: One refill 60oz bottle of Shout's Prewash Active Enzyme Stain Remover Refill

Everyday formula: works on a wide range of stains from food, drinks, makeup, grass, dirt, red wine, blood, and more

Clings, Penetrates, & Lifts: 50x more concentrated than in-wash powered when applied directly to stain

Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers

Spray, Rub, and Wash: our formula let's you treat the toughest stains and wash up to a week later
Shout Triple-Acting Laundry Stain Remover is tough on stains, but gentle on your color-fast machine-washable fabrics. It’s triple-acting formula Clings onto fabric stains in the washing cycle, Penetrates stains quickly once sprayed upon, and Lifts stains off of fabric. Shout Triple-Acting is 50x more concentrated than in-wash powder* and works on a wide range of everyday stains like food, grass, dirt, and blood. Safe for all colorfast washables and works in all water temperatures. Shout has the stain-fighting ingredients to break up and remove tough stains so you can live in the moment, and clean up later.

Items Details

Frequently Asked Questions

Is this formula safe for the whole family's clothing, including kids and baby items?

It is designed for use on colorfast, machine-washable family clothing and is used in households with children and pets daily as a prewash treatment that is rinsed out in the regular wash cycle.

Will it irritate sensitive skin after washing?

As a prewash treatment, the product is washed out during the normal laundry cycle along with your regular detergent, so residual contact with skin is minimal when used as directed.

Can I use it on baby clothes, cloth diapers, and nursery linens?

For colorfast machine-washable baby items, it can be used as a pretreatment. For items with specific care instructions or non-colorfast dyes, test in a hidden area first and follow the garment label.

Does it contain harsh chlorine bleach that could damage fabrics?

No. It is an enzyme-based pretreatment that lifts stains without chlorine bleach, which makes it safer for use on colored fabrics and gentler on fibers over time.

Is it safe to use in a home with cats and dogs who sleep on the treated laundry?

Once the item is washed and dried, the product is rinsed out with the regular detergent. Pets that come into contact with freshly laundered items are not exposed to the pretreatment.

Will it fade my dark or brightly colored clothing?

It is formulated to be safe for colorfast colored fabrics, so darks, brights, and patterned items can be pretreated without the color loss associated with harsher stain products.

Can I use it on delicate fabrics like silk or wool?

It is intended for machine-washable colorfast fabrics. For delicates, dry-clean-only items, or non-colorfast materials, follow the garment care label and avoid pretreatment unless the label permits.

Is the spray safe to breathe around when applying?

Use it in a well-ventilated area as you would with any household cleaning product. A quick spray and rub does not generate fumes and is appropriate for use in a standard laundry room with normal airflow.

How does an enzyme pretreatment compare to chlorine bleach for safety?

Chlorine bleach is corrosive, can fade colors, and produces fumes, while enzyme-based pretreatments are designed to lift stains without bleach-related risks on colorfast fabrics.

Is it safer for the washing machine than regular bleach?

Enzyme-based pretreatments do not carry the same corrosion and gasket-wear concerns as repeated chlorine bleach use, making them a gentler option for long-term washer care.

How does it compare to DIY stain treatments like hydrogen peroxide or vinegar?

DIY treatments can bleach colors and have inconsistent results, while a formulated enzyme spray is balanced for both whites and colorfast colors and engineered for reliable stain lift.

What if my child has eczema or very sensitive skin?

For households with skin sensitivities, run an extra rinse cycle on treated items and consult your pediatrician or dermatologist for product recommendations specific to your child's condition.

Is the 60oz bottle safe to store near other laundry products?

Yes. Store it upright with other laundry supplies at room temperature, away from direct sunlight, and out of reach of children and pets as you would any household cleaning product.

How do I use this stain remover spray for best results?

Spray the formula directly onto the stain until it is saturated, gently rub the fabric together or with a soft brush to work it in, and let it sit for at least a few minutes before laundering. You can also pretreat and wait up to a week before washing if needed.

Can I use it on both whites and colored clothing in the same load?

Yes. The formula is safe for both colorfast colored fabrics and machine-washable whites, so you can pretreat items and combine them in a single mixed load without separating by color.

Does it work in cold water, or do I need to use hot water?

It works effectively in all water temperatures, including cold, so you can use your normal energy-efficient wash settings without sacrificing stain-fighting performance.

Is this compatible with HE washing machines?

Yes. It is designed to work in both HE and standard washing machines, making it suitable for renters, homeowners, and anyone with either type of appliance.

Can I use it with my regular laundry detergent, or do I need a special detergent?

It works alongside your regular detergent. Apply the spray as a pretreatment before the wash, then use your usual detergent in the cycle for full cleaning.

What is included in the pack of 6, and what do I need to buy separately?

The pack of 6 includes six 60oz refill bottles of the stain remover. A spray trigger is not included with the refill format, so you can either reuse a trigger from a previous spray bottle or purchase a standard spray trigger separately if you want to spray directly from the refill.

Will it damage delicate fabrics like silk, wool, or rayon?

It is intended for machine-washable colorfast fabrics. For delicates, dry-clean-only items, or non-colorfast materials, test in an inconspicuous area first and follow the garment care label.

What happens if I leave the product on a stain longer than a week before washing?

The product is designed for up to one week of dwell time. For longer delays, reapply a fresh coat to the stain before laundering to refresh the formula's contact with the fabric.

What is the difference between a stain remover spray and an in-wash laundry booster?

An in-wash booster is added to the drum and diluted in the wash water, while a stain remover spray is applied directly to the fabric for concentrated, targeted contact with the stain before the wash cycle.

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