O'Keeffe's Working Hands Hand Cream – Hypoallergenic Unscented Formula Safe for Diabetes and Sensitive Skin, 3 oz
O'Keeffe's Working Hands Hand Cream – Hypoallergenic Unscented Formula Safe for Diabetes and Sensitive Skin, 3 oz
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Why you'll love it
- From the #1 hand cream brand in America, giving buyers confidence over lesser-known competitors
- Clinically proven to deliver an instant moisture boost and create a lasting protective moisture-locking layer
- Hypoallergenic, unscented, and non-greasy formula safe for sensitive skin and people with diabetes
- 3 oz travel size fits easily in bags, glove boxes, and work kits for on-the-go reapplication
- Bulk pack options (7, 8, 9 tubes) offer strong per-unit value for families and workplaces
- Sensible, fragrance-free formula that won't clash with perfumes, sanitizers, or workplace scent policies
Perfect for
- Repairing severely cracked, painful hands overnight after a day of manual labor or cold exposure
- Daily post-handwashing moisture seal to prevent moisture loss throughout the workday
- Bedtime intensive hand treatment for chronic dryness sufferers
- Bulk pack (7/8/9 tubes) for offices, households, or gifting to family members with dry hands
- Travel-size carry-on companion for airplane-cabin-dry-skin relief on trips
Product Information
Get your hands back: O’Keeffe’s Working Hands is a concentrated moisturizing cream that heals, relieves, soothes and repairs extremely cracked, dry hands; From the #1 hand cream brand in America*
Guaranteed relief for extremely dry hands: A hand cream that creates a protective layer on the skin's surface, locking in moisture and keeping even the driest skin hydrated and healthy
Hardworking skincare: O'Keeffe's Working Hands dry hand cream provides an instant moisture boost to relieve your discomfort and repair your dry skin to be full, moisturized and nourished
Recommended use: For best results, apply after hand washing, after bathing, and at bedtime - these are the most effective times for moisturizing extremely dry hands and skin
Hypoallergenic: O'Keeffe's Working Hands is unscented, non-greasy and safe for people with diabetes; Our 3 ounce tube is an ideal hand cream travel size so you can take your comfort on the go
O’Keeffe’s Working Hands Hand Cream is a concentrated, unscented hand cream that heals, relieves and repairs extremely dry, cracked hands. When used daily, O’Keeffe’s Working Hands Hand Cream is clinically proven to instantly boost moisture levels, help prevent further moisture loss, create a protective layer on the skin's surface that locks in moisture and keeps your skin hydrated, and make a difference you will feel within days. O’Keeffe’s offers a tube version of our moisturizing hand cream. Our tube formula offers the same results O’Keeffe’s jar users know and expect in the convenience of a tube! Whether you prefer a tube or jar, O’Keeffe’s Working Hands Hand Cream comes in both forms to provide relief. Click on the O'Keeffe's link at the top of this page to shop the O'Keeffe's Brand Store.
Items Details
Frequently Asked Questions
Is this hand cream safe for people with diabetes?
Yes. The formula is hypoallergenic, unscented, and non-greasy, and it is specifically called out as safe for people with diabetes, which makes it a reliable choice for diabetic skin care.
Is it safe to use on sensitive or allergy-prone skin?
Yes. The hypoallergenic, fragrance-free formula is designed to minimize the risk of irritation, which is why it is recommended by healthcare workers and people with reactive skin.
Will the unscented formula be safe around kids and pets?
Yes. Because it is fragrance-free, it does not release strong scents or volatile fragrances into the air, and the tube format keeps the product contained and out of reach when stored properly.
Does this cream interfere with the effectiveness of hand sanitizer?
No. You can apply the cream after sanitizer dries. The protective layer works with your sanitizer routine rather than against it, which matters in clinics and hospitals.
Is it safe to apply before putting on latex or nitrile gloves at work?
Yes, as long as you let the cream fully absorb first. The non-greasy finish means it will not break down most disposable gloves the way some oily lotions can.
Is this hand cream safe for a hospital or clinic setting?
Yes. The fragrance-free, non-greasy formula respects workplace scent policies and is safe for sensitive skin, which is why it is widely used in healthcare environments.
Is it safe for a nurse to apply between every patient?
Yes. Because it is non-greasy and fragrance-free, it is well-suited for nurses and clinicians who need to moisturize between hand hygiene steps without compromising grip or scent policies.
Can older adults with thin, fragile skin use this safely every day?
Yes. The hypoallergenic, gentle formula is appropriate for mature skin, and the concentrated moisture-locking layer is helpful for the chronic dryness that often comes with age.
Is it safe to leave on overnight without rinsing it off?
Yes. Overnight use is one of the recommended application timings, and the cream is designed to stay on the skin and continue locking in moisture while you sleep.
Is this hand cream safe to use alongside prescription skin creams?
In most cases, yes. The unscented, non-medicated formula is compatible with many prescription treatments, but as with any new product, it is wise to check with your dermatologist if you are on a strict regimen.
How does this compare to heavily perfumed department store hand creams?
Perfumed creams can trigger reactions in sensitive users and clash with workplace scent policies. O'Keeffe's is fragrance-free, hypoallergenic, and clinically proven for repair, which makes it a safer daily-use option.
Is it safer than a typical scented antibacterial hand lotion?
Yes. Scented antibacterial lotions can dry out skin further with fragrance and alcohol. O'Keeffe's focuses on clinically proven moisture repair without fragrance, which is gentler for repeated use.
How does it compare to a baby hand cream for adults with sensitive skin?
Baby creams are gentle but mild, which is often not enough for severely dry, cracked adult hands. O'Keeffe's is a concentrated repair cream that is still hypoallergenic and unscented, giving you strength without irritation risk.
I worry about harsh chemicals. Is this formula clean and simple?
The formula is hypoallergenic, unscented, and non-greasy, with no added fragrance to irritate sensitive skin, and the ingredient list is intentionally short and focused on moisture repair.
What if my skin reacts the first time I use it?
Stop use and rinse with water. While reactions are uncommon with the hypoallergenic formula, the company offers customer support to help troubleshoot, and unscented options are gentler for reactive skin.
Is a 3 oz tube safe to keep in a car in hot weather?
The tube is durable for normal use, but as with most creams, very high heat can affect texture. Many users keep one in the glove box and bring a backup inside during heat waves.
How do I apply O'Keeffe's Working Hands Hand Cream for the best results?
Apply a small amount to dry hands as needed, especially after hand washing, bathing, and at bedtime. The cream is concentrated, so a little goes a long way, and it absorbs quickly without leaving a greasy residue.
How often should I reapply it during the day?
Most people apply it after each hand washing and once at bedtime. In harsher conditions, such as outdoor work or long flights, you can reapply whenever your hands feel tight or dry.
Can I use it on other dry areas like feet, elbows, or knees?
Yes. Although it is formulated and marketed for hands, the same concentrated, fragrance-free repair cream is commonly used on feet, elbows, knees, and any other small area of severely dry skin.
Is the 3 oz tube compatible with standard toiletry bags and travel kits?
Yes. The 3 oz size is designed to fit standard toiletry bags, quart-size carry-on pouches, glove boxes, and most work kits, and the slim tube format lays flat for easy packing.
Does the tube work with the same formula as the jar?
Yes. The same trusted O'Keeffe's Working Hands formula is available in both tube and jar, so you can choose your preferred packaging without changing the results.
What comes in the box when I order a single 3 oz tube?
Each order of a single 3 oz tube includes one tube of O'Keeffe's Working Hands Hand Cream. Multi-pack orders include 7, 8, or 9 individually wrapped tubes depending on the option you select, and no additional accessories are required to use the product.
Is this hand cream safe for people with eczema or very reactive skin?
The hypoallergenic, fragrance-free formula is designed to minimize irritation, and many people with sensitive skin use it successfully. That said, if you have a specific skin condition, it is always wise to patch test first or check with your dermatologist.
How should I store the tube to keep it fresh?
Store the tube at room temperature with the cap closed, away from direct sunlight and extreme heat. Under normal conditions, the formula stays fresh for several years, and the tube is easy to take with you wherever you go.
What is the difference between a hand cream and a hand lotion?
Hand lotions are typically light, water-based moisturizers designed for everyday hydration, while O'Keeffe's Working Hands is a concentrated repair cream clinically proven to create a protective moisture-locking layer, which is better suited for severely dry, cracked hands.
